Relieves external itching and irritation due to a vaginal yeast infection. ABOUT MICONAZOLE NITRATE VAGINAL INSERT (1200 MG) AND MICONAZOLE NITRATE CREAM (2%): Compare to the active ingredients in MONISTAT 1 Combination Pack. Miconazole Nitrate Vaginal Insert (1200 mg) and Miconazole Nitrate Cream (2%) cures most vaginal yeast infections and relieves associated external itching and irritation. This combination pack provides 1 vaginal softgel insert with 1 applicator, plus external cream for itch relief.